Howard Lin*, Vivekanudeep Karri*, Jessica Velazquez, Akanksha Batajoo, Deevyashali Parekh, Whitney Stanton, Harshal Abhyankar, Nader K El-Mallawany, Jennifer Agrusa, Olive Eckstein, Nitya Gulati, Jeffrey Schwartz, Wendy Woods-Stafford, Jaime Boyd, Anikit Saha, Carl E Allen, Kenneth L McClain. “Clinical, radiological and molecular responses to combination chemotherapy with MAPK pathway inhibition in relapsed and refractory Langerhans cell histiocytosis.” British journal of haematology. 2024 March 19. PMID: 38501390.
Howard Lin*, Deevyashali Parekh*, Akanksha Batajoo, Erin Peckham-Gregory, Vivekanudeep Karri, Whitney Stanton, Brooks Scull, Ryan Fleishmann, Nader El-Mallawany, Olive S Eckstein, Zachary D Prudowsky, Nitya Gulati, Jennifer E Agrusa, Asra Z Ahmed, Roland Chu, Matthew S Dietz, Stanton C Goldman, Michael D Hogarty, Hamayun Imran, Stefanos Intzes, Jenny M Kim, Lisa M Kopp, Carolyn Fein Levy, Philip Neff, Pallavi M Pillai, Bryan A Sisk, Deborah E Schiff, Angela D Trobaugh-Lotrario, Kelly Walkovich, Kenneth L McClain, Carl Allen. “Clofarabine monotherapy in aggressive, relapsed and refractory Langerhans cell histiocytosis.” British journal of haematology. 2024 March 19. PMID: 38501389.
C. Matthias Wilk, Flurin Cathomas, Orsolya Török, Jessica Le Berichel, Matthew Park, Camille Bigenwald, George Heaton, Pauline Hamon, Leanna Troncoso, Brooks Scull, Diana Dangoor, Aymeric Silvin, Ryan Fleischmann, Meriem Belabed, Howard Lin, Elias Merad Taouli, Steffen Boettcher, Long Li, Antonio Aubry, Markus G Manz, Julia K Kofler, Zhenyu Yue, Sergio Lira, Florent Ginhoux, John Crary, Kenneth McClain, Jennifer Picarsic, Scott Russo, Carl Allen, Miriam Merad. “Circulating senescent myeloid cells infiltrate the brain and cause neurodegeneration in histiocytic disorders.” Immunity. 2023. PMID: 38091952.
Ashley Geerlinks, Brooks Scull, Christa Krupski, Ryan Fleischmann, Michael A Pulsipher, Mary Eapen, James A Connelly, Catherine M Bollard, Sung-Yun Pai, Christine Duncan, Leslie S Kean, K Scott Baker, Lauri Burroughs, Jeffrey R Andolina, Shalini Shenoy, Philip Roehrs, Rabi Hanna, Julie-An Talano, Kirk Schultz, Elizabeth Stenger, Howard Lin, Adi Zoref-Lorenz, Kenneth L McClain, Michael B Jordan, Tsz-Kwong Man, Carl Allen, Rebecca Marsh. “Alemtuzumab and CXCL9 levels predict likelihood of sustained engraftment after reduced intensity conditioning HCT.” Blood Adv. 2023 April 12. Pubmed PMID: 37042921.
Howard Lin, Brooks Scull, Baruch Goldberg, Harshal Abhyankar, Olive Eckstein, Daniel Zinn, Joseph Lubega, Jennifer Agrusa, Nader K El-Mallawanay, Nitya Gulati, Lisa Forbes, Ivan Chinn, Rikhia Chakraborty, Jessica Velazquez, Jordana Goldman, Dalia Bashir, Fong Wilson Lam, Eyal Muscal, Michael Henry, Jay Greenberg, Stephan Ladisch, Michelle Hermiston, Lauren Meyer, Michael Raymond Jeng, Ahmed Naqvi, Kenneth McClain, Trung Nguyen, Hector Wong, Tsz-Kwong Man, Michael B. Jordan, Carl Allen. “IFN-γ Signature in the Plasma Proteome Distinguishes Pediatric Hemophagocytic Lymphohistiocytosis from Sepsis and SIRS.” Blood Adv. 2021 Aug 30. Pubmed PMID: 34461635.
Camille Bigenwald, Jessica Le Berichel, C. Matthias Wilk, Rikhia Chakraborty, Steven Chen, Alexandra Tabachnikova, Rebecca Mancusi, Harshal Abhyankar, Maria Casanova-Acebes, Ilaria Laface, Guray Akturk, Jenielle Jobson, Zoi Karoulia, Jerome C. Martin, John Grout, Anahita Rafiei, Howard Lin, Markus Manz, Alessia Baccarini, Poulikos Poulikakos, Brian Brown, Sacha Gnjatic, Amaia Lujambio, Kenneth McClain, Jennifer Picarsic, Carl Allen, Miriam Merad. “BRAFV600E-induced senescence drives Langerhans cell histiocytosis pathophysiology.” Nat Med. 2021 May 6. Pubmed PMID: 33958797.
Jennifer Agrusa, Brooks Scull, Harshal Abhyankar, Howard Lin, Nmazuo Ozuah, Rikhia Chakraborty, Olive Eckstein, Nitya Gulati, Elmoataz Abdel Fattah, Nader K El-Mallawany, Rayne Rouce, ZoAnn Dreyer, Julienne Brackett, Judith Margolin, Joseph Lubega, Terzah Horton, Catherine Bollard, Monica Gramatges, Kala Kamdar, Kenneth McClain, Tsz-Kwong Man, Carl Allen. “Defining the Inflammatory Plasma Proteome in Pediatric Hodgkin Lymphoma.” Cancers (Basel). 2020 Dec 2. Pubmed PMID: 33276546.
Karen Phaik Har Lim, Paul Milne, Michael Poidinger, Kaibo Duan, Howard Lin, Naomi McGovern, Harshal Abhyankar, Daniel Zinn, Olive Eckstein, Rikhia Chakraborty, Amel Sengal, Brooks Scull, Evan Newell, Miriam Merad, Kenneth McClain, Tsz-Kwong Man, Florent Ginhoux, Matthew Collin, Carl Allen. “Circulating CD1c+ myeloid dendritic cells are precursors to Langerhans cell histiocytosis (LCH) lesion CD1a+CD207+ cells.” Blood Adv. 2020 Jan 4. Pubmed PMID: 31899802
Olive Eckstein, Johannes Visser, Daniel Zinn, Erin Peckham-Gregory, Howard Lin, Michael M. Henry, Bruce Morland, Carolyn Fein Levy, Ashish Kumar, Deborah Schiff, Nicole Karras, Roland L. Chu, Oussama Abla, Nobuko Hijiya, Sun Young Kim, Patrick Campbell, Wendy Woods-Swafford, Lorimar Ramirez, Cristina Fernandes, Matthew Murray, Harshal Abhyankar, Rikhia Chakraborty, Brooks Scull, Andrew C. Sher, Michelle Hermiston, Michael Hogarty, Michael Jordan, Miriam Merad, Barrett Rollins, Kenneth McClain, Tsz-Kwong Man, Carlos Rodriguez-Galindo, Carl Allen. “Clinical responses and persistent BRAF V600E+ blood cells in children with LCH treated with MAPK pathway inhibition.” Blood. 2019 Feb 4. Pubmed PMID: 30718231
Kenneth McClain, Jennifer Picarsic, Rikhia Chakraborty, Daniel Zinn, Howard Lin, Harshal Abhyankar, Brooks Scull, Albert Shih, Karen Phaik Har Lim, Olive Eckstein, Joseph Lubega, Tricia Peters, Walter Olea, Thomas Burke, Nabil Ahmed, John Hicks, Brandon Tran, Jeremy Jones, Robert Dauser, Michael Jeng, Robert Baiocchi, Deborah Schiff, Stanton Goldman, Kenneth Heym, Harry Wilson, Benjamin Carcamo, Ashish Kumar, Carlos Rodriguez-Galindo, Nicholas Whipple, Patrick Campbell, Geoffrey Murdoch, Julia Kofler, Simon Heales, Marian Malone, Randy Woltjer, Joseph Quinn, Paul Orchard, Michael Kruer, Ronald Jaffe, Markus Manz, Sergio Lira, Williams Parsons, Miriam Merad, Tsz-Kwong Man, Carl Allen. "CNS Langerhans cell histiocytosis: Common hematopoietic origin for LCH-associated neurodegeneration and mass lesions." Cancer. 2018 April 6. Pubmed PMID: 29624648
Brandon Hogstad, Marie-Luise Berres, Rikhia Chakraborty, Jun Tang, Camille Bigenwald, Madhavika Serasinghe, Karen Phaik Har Lim, Howard Lin, Tsz-Kwong Man, Romain Remark, Samantha Baxter, Veronika Kana, Stefan Jordan, Zoi Karoulia, Wing-hong Kwan, Marylene Leboeuf, Elisa Brandt, Helene Salmon, Kenneth McClain, Poulikos Poulikakos, Jerry Chipuk, Willem Mulder, Carl Allen, and Miriam Merad. "RAF/MEK/ERK pathway suppresses dendritic cell migration and traps dendritic cells in LCH lesions." Journal of Experimental Medicine. 2017 Dec 20. Pubmed PMID: 29263218
Daniel Zinn, Amanda Grimes, Howard Lin, Rachel Bingham, Olive Eckstein, Carl Allen, Kenneth McClain. "Hydroxyurea: a new old therapy for Langerhans cell histiocytosis." Blood. 2016 Nov 17. Pubmed PMID: 27688802
